Aumitin
目录号: A18838
Autophagy 抑制剂
Aumitin 是一种自噬抑制剂,针对的是线粒体复合体 I。Aumitin 可以剂量依赖性地抑制由饥饿和雷帕霉素诱导的自噬,其半抑制浓度(IC50)分别为0.12 微米和0.24 微米。
Discription | Aumitin is an autophagy inhibitor, targeting mitochondrial complex I. Aumitin inhibits starvation- and rapamycin induced autophagy dose dependently with IC50s of 0.12 μM and 0.24 μM, respectively. |
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目录号 | A18838 |
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分子式 | C24H20ClN5O |
分子量 | 429.91 |
CAS号 | 946293-78-3 |
SMILES | O=C(NC1=CC=C(NC2=NC(NC3=CC=CC=C3)=CC(C)=N2)C=C1)C4=CC=CC=C4Cl |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2