Auristatin E

Name: Auristatin E
SKU: A21269
Price: 140 CNY
Rating: 5 (288 reviews)

目录号: A21269

cytotoxic tubulin modifier

Auristatin E 是一种具有强效和选择性抗肿瘤活性的细胞毒性微管蛋白修饰剂；是 MMAE 的类似物和抗体药物偶联物中的细胞毒素。Auristatin E 通过阻断微管蛋白的聚合来抑制细胞分裂。

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Grouped product items
规格	价格	库存
1mg	¥140.00	现货
5mg	¥280.00	现货
10mg	¥455.00	现货
25mg	¥875.00	现货
50mg	¥1,505.00	现货
100mg	¥2,905.00	现货
250mg	¥5,250.00	现货
500mg	¥8,400.00	现货
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Data Sheet

SDS

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生物活性

Discription

Auristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates. Auristatin E inhibits cell division by blocking the polymerisation of tubulin.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A21269
分子式	C40H69N5O7
分子量	732.01
CAS号	160800-57-7
SMILES	CC(C)[C@H](N(C)C)C(N[C@H](C(N([C@@H]([C@@H](C)CC)[C@@H](CC(N1CCC[C@@]1([H])[C@H](OC)[C@@H](C)C(N[C@H](C)[C@H](C2=CC=CC=C2)O)=O)=O)OC)C)=O)C(C)C)=O
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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