Aurora A Inhibitor I 是一种强效且选择性的 Aurora A 激酶 (AurA) 抑制剂，其 IC50 值为 3.4 nM（针对 Aurora A），并且对 Aurora B 具有极高的选择性，高达 1000 倍；这是一种有用的工具化合物，用于研究 Aurora A 激酶 在细胞中的作用。
Aurora A Inhibitor I is a potent and selective inhibitor of Aurora A kinase (AurA), with IC50 values to be 3.4 nM (Aurora A) and unusually high selectivity 1000 fold against Aurora B; a useful tool compound for investigating the cellular role of Aurora A kinases.
Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
溶解性数据
In vitro (25°C)
DMSO
105 mg/mL (178.54 mM)
Water
Insoluble
Ethanol
Insoluble
In vivo
5%DMSO+40%PEG300+5%Tween80+50%ddH2O
1.18 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
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