Aurora Kinase Inhibitor 3

Name: Aurora Kinase Inhibitor 3
SKU: A19448

目录号: A19448

Aurora A kinase inhibitor

Aurora Kinase Inhibitor 3 Chemical Structure

CAS NO. 879127-16-9

Aurora Kinase Inhibitor 3 is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50>10 μM.

库存：现货

规格	价格	数量
1 mg	￥ 567.00
5 mg	￥ 1,701.00
10 mg	￥ 2,898.00
50 mg	￥ 8,694.00

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生物活性

Aurora Kinase Inhibitor 3 is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50>10 μM.

溶解度 *

In vitro	DMSO	82 mg/mL (198.35 mM)
	Water	Insoluble
	Ethanol	5 mg/mL (12.09 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	24.19 mL	120.95 mL	241.9 mL
0.5 mM	4.84 mL	24.19 mL	48.38 mL
1 mM	2.42 mL	12.09 mL	24.19 mL
5 mM	0.48 mL	2.42 mL	4.84 mL

*The above data is based on the productmolecular weight 413.4. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A19448
M. Wt	413.4
Formula	C21H18F3N5O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	879127-16-9
SMILES	O=C(C1CC1)NC2=CC=CC(NC3=NC=CC(NC4=CC=CC(C(F)(F)F)=C4)=N3)=C2