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Aurora Kinase Inhibitor 3

目录号: A19448
Aurora A kinase 抑制剂
Aurora Kinase Inhibitor 3 是一种强效且选择性的 Aurora A kinase 抑制剂,其 IC50 为 42 nM,对 EGFR 的抑制作用较弱,IC50 大于 10 μM。
Grouped product items
规格 价格 库存 数量
1mg
¥455.00
现货
2mg
¥630.00
现货
5mg
¥1,330.00
现货
10mg
¥2,135.00
现货
25mg
¥3,640.00
现货
50mg
¥5,180.00
现货
100mg
¥6,860.00
现货
200mg
¥9,625.00
现货
10mM * 1mL in DMSO
¥1,540.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription Aurora Kinase Inhibitor 3 is a strong and selective Aurora A kinase inhibitor with an IC50 of 42 nM, and weakly inhibits EGFR with an IC50>10 μM.
Targets
Target Value
产品信息
目录号 A19448
分子式 C21H18F3N5O
分子量 413.4
CAS号 879127-16-9
SMILES O=C(C1CC1)NC2=CC=CC(NC3=NC=CC(NC4=CC=CC(C(F)(F)F)=C4)=N3)=C2
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 82 mg/mL (198.35 mM)
Water Insoluble
Ethanol 5 mg/mL (12.09 mM)
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 24.19 mL 120.95 mL 241.9 mL
0.5 mM 4.84 mL 24.19 mL 48.38 mL
1 mM 2.42 mL 12.09 mL 24.19 mL
5 mM 0.48 mL 2.42 mL 4.84 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

  • Mass

    Concentration

    Volume

    Molecular Weight

Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

  • C1

    V1

    C2

    V2

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