Avibactam sodium
目录号: A17306
non-β-lactam β-lactamase 抑制剂
Avibactam sodium (NXL-104) 是一种共价和可逆的非-β-内酰胺类 β-内酰胺酶抑制剂，它能抑制 β-内酰胺酶 TEM-1 和 CTX-M-15，其 IC50 分别为 8 nM 和 5 nM。
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生物活性
| Discription | Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC50s of 8 nM and 5 nM, respectively. |
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产品信息
| 目录号 | A17306 |
|---|---|
| 分子式 | C7H10N3NaO6S |
| 分子量 | 287.23 |
| CAS号 | 1192491-61-4 |
| SMILES | O=S(ON1[C@]2([H])CC[C@@H](C(N)=O)[N@@](C2)C1=O)([O-])=O.[Na+] |
| 其他名称 | NXL-104 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 49 mg/mL (170.59 mM) | |
| Water | 49 mg/mL (170.59 mM) | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 34.82 mL | 174.08 mL | 348.15 mL |
| 0.5 mM | 6.96 mL | 34.82 mL | 69.63 mL |
| 1 mM | 3.48 mL | 17.41 mL | 34.82 mL |
| 5 mM | 0.7 mL | 3.48 mL | 6.96 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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