Axitinib

Name: Axitinib
SKU: A10103
Price: 175 CNY
Rating: 5 (5 reviews)

目录号: A10103

VEGFR 抑制剂

5 篇发表文献

Axitinib 是一种小分子酪氨酸激酶抑制剂，它能抑制多个靶点，包括 VEGFR-1、VEGFR-2、VEGFR-3、血小板源生长因子受体（PDGFR）和 cKIT (CD117)。

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Grouped product items
规格	价格	库存
25mg	¥175.00	现货
50mg	¥245.00	现货
100mg	¥385.00	现货
250mg	¥560.00	现货
500mg	¥1,015.00	现货
1g	¥1,470.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Axitinib发表的5篇文献

Sophie J. Bakri, .et al. , PLoS One, 2024, 19(6): e0304782 PMID: 38833447

Hongwan Ding, .et al. , Toxicol Appl Pharmacol, 2024, May:486:116950 PMID: 38701902

Hongwan Ding, .et al. , Research Square, 2023, Dec 28

Vijaya Bharti, .et al. , Cell Rep, 2022, Dec 20;41(12):111826 PMID: 36543138

Youcef M. Rustum, .et al. , Int J Mol Sci, 2018, Nov; 19(11): 3378 PMID: 30380599

生物活性

Discription

Axitinib is a small molecule tyrosine kinase inhibitor,which inhibits multiple targets, including VEGFR-1, VEGFR-2, VEGFR-3, platelet derived growth factor receptor (PDGFR), and cKIT (CD117).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10103
分子式	C22H18N4OS
分子量	386.5
CAS号	319460-85-0
SMILES	CNC(=O)C1=CC=CC=C1SC2=CC3=C(C=C2)C(=NN3)/C=C/C4=CC=CC=N4
其他名称	AG 013736
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	Warmed: 30 mg/mL (77.62 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.87 mL	129.37 mL	258.73 mL
0.5 mM	5.17 mL	25.87 mL	51.75 mL
1 mM	2.59 mL	12.94 mL	25.87 mL
5 mM	0.52 mL	2.59 mL	5.17 mL

Useful Calculator

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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