AY254

Name: AY254
SKU: A23881
Price: 5250 CNY
Rating: 5 (288 reviews)

目录号: A23881

PAR2 激动剂

AY254 是 AY77 的类似物。AY254 是一种 ERK-偏向的 PAR2 激动剂，具有 2 nM 的 EC50。AY254 可缓解细胞因子诱导的 caspase 3/8 激活。AY254 还通过 PAR2-ERK1/2 信号传导促进划痕伤口愈合，并诱导 IL-8 分泌。

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规格	价格	库存
1mg	¥5,250.00	现货
5mg	¥6,755.00	现货
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Data Sheet

SDS

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生物活性

Discription	AY254 is an analogue of AY77. AY254 is ERK-biased PAR2 agonist with an EC50 of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling.

产品信息

目录号	A23881
分子式	C30H49N9O6
分子量	631.77
CAS号	2093408-03-6
Sequence	{5-Isoxazolylcarbonyl-Cha}-{Chg}-Ala-Arg-NH2
Sequence shortening	{5-Isoxazolylcarbonyl-Cha}-{Chg}-AR-NH2

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