AZ 3146

Name: AZ 3146
SKU: A11170
Price: 210 CNY
Rating: 5 (7 reviews)

目录号: A11170

Mps1 抑制剂

7 篇发表文献

AZ 3146 是一种强效且选择性的单极纺锤体1 (Mps1) 激酶抑制剂（IC50 = 35 nM）。它干扰染色体排列，并能绕过纺锤体组装检查点，同时抑制 Mad1、Mad2 和着丝粒蛋白E (CENP-E) 的招募到着丝粒。

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥315.00	现货
10mg	¥525.00	现货
25mg	¥1,085.00	现货
50mg	¥1,645.00	现货
100mg	¥3,115.00	现货
*10mM 1mL in DMSO**	¥420.00	现货
更大包装	更多折扣

大包装询价

Notify me when the price drops

全国免运费, 顺丰次日达

重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AZ 3146发表的7篇文献

Junna Tanaka, .et al. , Cell Signal, 2024, Jul:119:111172 PMID: 38604342

Ryuzaburo Yuki, .et al. , Eur J Pharmacol, 2024, Jan 15:963:176229 PMID: 38072041

Ryoko Ota, .et al. , Cell Signal, 2023, Sep;109:110764 PMID: 37315749

Ryuzaburo Yuki, .et al. , J Cell Mol Med, 2021, Feb;25(3):1677-1687 PMID: 33465289

Yamagishi A, .et al. , Int J Mol Sci, 2020, Feb 5;21(3) PMID: 32033461

Kakihana A, .et al. , FASEB J, 2018, Nov 29:fj201801369R PMID: 30496702

Suzuki M, .et al. , Anticancer Res, 2016, Jun;36(6):2783-92 PMID: 27272789

生物活性

Discription

AZ 3146 is a potent and selective monopolar spindle 1 (Mps1) kinase inhibitor (IC50 = 35 nM). It interferes with chromosome alignment and overrides spindle assembly checkpoint and also Inhibits the recruitment of Mad1, Mad2 and centromere protein E (CENP-E) to kinetochores.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11170
分子式	C24H32N6O3
分子量	452.55
CAS号	1124329-14-1
SMILES	CN1CCC(CC1)OC2=CC(=C(C=C2)NC3=NC=C4C(=N3)N(C(=O)N4C)C5CCCC5)OC
其他名称	AZ-3146
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	27 mg/mL (59.66 mM)
	Water	Insoluble
	Ethanol	87 mg/mL (192.24 mM)
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.1 mL	110.49 mL	220.97 mL
0.5 mM	4.42 mL	22.1 mL	44.19 mL
1 mM	2.21 mL	11.05 mL	22.1 mL
5 mM	0.44 mL	2.21 mL	4.42 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Keywords: 购买 AZ 3146 | AZ 3146 供应商 | AZ 3146 花费 | AZ 3146 生产商 | 订购 AZ 3146 | AZ 3146 代理商 | 购买 1124329-14-1 | 1124329-14-1 供应商 | 1124329-14-1 花费 | 1124329-14-1 生产商 | 订购 1124329-14-1 | 1124329-14-1 代理商