微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
AZ-960是一种有效的，选择性的和ATP竞争性的JAK2抑制剂，在体外抑制JAK2激酶的Ki为0.45 nM，并诱导成年T细胞白血病（ATL）细胞的生长停滞和凋亡
靶点信息
| JAK2 | JAK2 | |||
| 0.45 nM(Ki) | <3 nM |
| In vitro | DMSO | 70 mg/mL (197.54 mM) | |
| Water | Insoluble | ||
| Ethanol | 3 mg/mL (8.46 mM) | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 28.22 mL | 141.08 mL | 282.17 mL |
| 0.5 mM | 5.64 mL | 28.22 mL | 56.43 mL |
| 1 mM | 2.82 mL | 14.11 mL | 28.22 mL |
| 5 mM | 0.56 mL | 2.82 mL | 5.64 mL |
*The above data is based on the productmolecular weight 354.4 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A10104 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 354.4 |
| Formula | C18H16F2N6 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 905586-69-8 |
| Synonyms | AZ960 |
| SMILES | CC1=CC(=NN1)NC2=C(C=C(C(=N2)N[C@@H](C)C3=CC=C(C=C3)F)C#N)F |
产品标签
Product Questions
Product Questions
No Questions
您还可能对下列产品感兴趣
Pexidartinib (PLX3397)
Pexidartinib (PLX3397)是KIT，CSF1R和FLT3的小分子酪氨酸激酶（RTK）抑制剂，具有潜在的抗肿瘤活性。
SGI-1776 (free base)
SGI-1776 (free base)是Pim1的一种新型ATP竞争性抑制剂，在无细胞试验中的IC50为7 nM，选择性是Pim2和Pim3的50倍和10…
VX-680 (MK-0457, Tozasertib)
VX-680 (MK-0457,Tozasertib)是一种有效的选择性Aurora激酶小分子抑制剂。
BMS-911543
BMS-911543是一种有效的、选择性JAK2小分子抑制剂。
Filgotinib
Filgotinib是一种选择性的JAK1抑制剂，对于JAK1，JAK2，JAK3和TYK2的IC50分别为10 nM，28 nM，810 nM和116 nM。
Keywords:购买 AZ-960 | AZ-960 供应商 | 订购 AZ-960 | AZ-960 价格 | AZ-960 生产商 | 订单 AZ-960 | AZ-960 代理商 | 购买 905586-69-8| 905586-69-8 供应商 | 订购 905586-69-8 | 905586-69-8 价格 | 905586-69-8 生产商 | 订单 905586-69-8 | 905586-69-8 代理商|buy AZ-960 | AZ-960 Supplier | purchase AZ-960 | AZ-960 cost | AZ-960 manufacturer | order AZ-960 | AZ-960 distributor | buy 905586-69-8| 905586-69-8 Supplier | purchase 905586-69-8 | 905586-69-8 cost | 905586-69-8 manufacturer | order 905586-69-8 | 905586-69-8 distributor