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AZ1495 (compound 28) is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 25.94 mL | 129.7 mL | 259.4 mL |
| 0.5 mM | 5.19 mL | 25.94 mL | 51.88 mL |
| 1 mM | 2.59 mL | 12.97 mL | 25.94 mL |
| 5 mM | 0.52 mL | 2.59 mL | 5.19 mL |
*The above data is based on the productmolecular weight 385.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A19512 |
|---|---|
| M. Wt | 385.5 |
| Formula | C21H31N5O2 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 2196204-23-4 |
| Synonyms | AZ 1495, AZ-1495 |
| SMILES | C1(C(C2CCOCC2)=CN3)=C3N=CN=C1N[C@@H]4CC[C@@H](N5CCOCC5)CC4 |
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