AZ1495
目录号: A19512
IRAK4 inhibitor
AZ1495(化合物28)是一种口服活性的白细胞介素-1受体相关激酶4(IRAK4)抑制剂,其IC50值分别针对IRAK4和IRAK1为5 nM和23 nM。
Discription | AZ1495 (compound 28) is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. | ||
---|---|---|---|
Targets |
|
目录号 | A19512 |
---|---|
分子式 | C21H31N5O2 |
分子量 | 385.5 |
CAS号 | 2196204-23-4 |
SMILES | C1(C(C2CCOCC2)=CN3)=C3N=CN=C1N[C@@H]4CC[C@@H](N5CCOCC5)CC4 |
其他名称 | AZ 1495, AZ-1495 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2