AZ505
目录号: A13061
SMYD2 抑制剂
AZ505 是一种强效且高度选择性的 SMYD2 抑制剂(IC50=0.12 μM),具有潜在的抗癌活性,其选择性是 SMYD3(IC50>83.3 μM)、DOT1L(IC50>83.3 μM)、EZH2(IC50>83.3 μM)的600倍以上。
Discription | AZ505 is a potent and highly selective inhibitor of the oncogenic protein SMYD2(IC50=0.12 μM) with potential anticancer activity, >600 fold than SMYD3(IC50>83.3 μM); DOT1L(IC50>83.3 μM);EZH2(IC50>83.3 μM). | |||||
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Cell Research |
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目录号 | A13061 |
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分子式 | C29H38Cl2N4O4 |
分子量 | 577.54 |
CAS号 | 1035227-43-0 |
SMILES | C1CCC(CC1)N(CCNCCC2=C3C(=C(C=C2)O)NC(=O)CO3)C(=O)CCNCCC4=CC(=C(C=C4)Cl)Cl |
其他名称 | AZ 505, AZ-505 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2