产品详情
AZ505是一种有效且高度选择性的致癌蛋白SMYD2抑制剂(IC50 = 0.12μM),具有潜在的抗癌活性,是SMYD3(IC50> 83.3μM)的600倍以上; DOT1L(IC50> 83.3μM); EZH2(IC50> 83.3μM)。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 17.31 mL | 86.57 mL | 173.15 mL |
0.5 mM | 3.46 mL | 17.31 mL | 34.63 mL |
1 mM | 1.73 mL | 8.66 mL | 17.31 mL |
5 mM | 0.35 mL | 1.73 mL | 3.46 mL |
*The above data is based on the productmolecular weight 577.54. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A13061 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 577.54 |
Formula | C29H38Cl2N4O4 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1035227-43-0 |
Synonyms | AZ 505, AZ-505 |
SMILES | C1CCC(CC1)N(CCNCCC2=C3C(=C(C=C2)O)NC(=O)CO3)C(=O)CCNCCC4=CC(=C(C=C4)Cl)Cl |
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