AZ628

Name: AZ628
SKU: A11063
Price: 210 CNY
Rating: 5 (288 reviews)

目录号: A11063

Raf 抑制剂

AZ628 是一种 RAF 抑制剂，其 IC50 值为：对 BRAF V600E 和野生型 CRAF 约 30 nM，对野生型 BRAF 为 100 nM。

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Grouped product items
规格	价格	库存
2mg	¥210.00	现货
5mg	¥385.00	现货
10mg	¥595.00	现货
25mg	¥1,225.00	现货
50mg	¥1,960.00	现货
100mg	¥2,555.00	现货
*10mM 1mL in DMSO**	¥385.00	现货
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Data Sheet

SDS

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生物活性

Discription

AZ628 is a RAF inhibitor with IC50 values: ca 30 nM for BRAF V600E and wild-type CRAF and 100 nM for wild-type BRAF.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11063
分子式	C27H25N5O2
分子量	451.5
CAS号	878739-06-1
SMILES	CC1=C(C=C(C=C1)NC(=O)C2=CC(=CC=C2)C(C)(C)C#N)NC3=CC4=C(C=C3)N=CN(C4=O)C
其他名称	AZ-628
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	80 mg/mL (177.17 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	5 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	22.15 mL	110.74 mL	221.48 mL
0.5 mM	4.43 mL	22.15 mL	44.3 mL
1 mM	2.21 mL	11.07 mL	22.15 mL
5 mM	0.44 mL	2.21 mL	4.43 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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