AZD-8529

Name: AZD-8529
SKU: A20045
Price: 350 CNY
Rating: 5 (288 reviews)

目录号: A20045

mGluR2 modulator

AZD-8529 是一种强效、高度选择性且口服生物利用度高的 mGluR2 的正向异构调节剂，其 EC50 为 285 nM，并且在 mGluR1, 3, 4, 5, 6, 7, 8 亚型上的浓度为 20-25 M 时不显示正向异构调节剂反应。

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Grouped product items
规格	价格	库存
1mg	¥350.00	现货
5mg	¥1,050.00	现货
10mg	¥1,785.00	现货
25mg	¥3,990.00	现货
50mg	¥6,930.00	现货
100mg	¥12,075.00	现货
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Data Sheet

SDS

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生物活性

Discription

AZD-8529 is a potent, highly selective and orally bioavailable positive allosteric modulator of mGluR2, with an EC50 of 285 nM, and shows no positive allosteric modulator responses at 20-25 M on the mGluR1, 3, 4, 5, 6, 7, and 8 subtypes.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A20045
分子式	C24H24F3N5O3
分子量	487.47
CAS号	1092453-15-0
SMILES	O=C1C2=C(C)C=C(C3=NC(CN4CCNCC4)=NO3)C=C2CN1CC5=CC=C(OC(F)(F)F)C=C5
其他名称	AZD8529, AZD 8529
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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