AZD1152-HQPA (Barasertib)

Name: AZD1152-HQPA (Barasertib)
SKU: A10109
Price: 245 CNY
Rating: 5 (2 reviews)

目录号: A10109

Aurora Kinase B 抑制剂

2 篇发表文献

AZD 1152-HQPA 是一种高效且选择性的 Aurora B 抑制剂，其 Ki 值分别为 0.36 nM（Aurora B）和 1369 nM（Aurora A），并且相对于其他50种激酶具有高度的特异性。

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Grouped product items
规格	价格	库存
5mg	¥245.00	现货
10mg	¥385.00	现货
25mg	¥770.00	现货
50mg	¥1,400.00	现货
100mg	¥2,730.00	现货
500mg	¥6,860.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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Data Sheet

SDS

Other Forms of AZD1152-HQPA (Barasertib)

AZD1152

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AZD1152-HQPA (Barasertib)发表的2篇文献

Sakamoto K, .et al. , Leukemia, 2018, May 23 PMID: 29795241

Jennifer M. Sahni, .et al. , J Biol Chem, 2016, Nov 4; 291(45): 23756-23768 PMID: 27650498

生物活性

Discription

AZD 1152-HQPA is a highly potent and selective inhibitor of Aurora B, with Ki values to be 0.36 (Aurora B) and 1369 nM (Aurora A) respectively and has a high specificity versus a panel of 50 other kinases.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10109
分子式	C26H30FN7O3
分子量	507.7
CAS号	722544-51-6
SMILES	CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	93 mg/mL (183.23 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (5.91 mM)
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	6 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.7 mL	98.48 mL	196.97 mL
0.5 mM	3.94 mL	19.7 mL	39.39 mL
1 mM	1.97 mL	9.85 mL	19.7 mL
5 mM	0.39 mL	1.97 mL	3.94 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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