AZD1152

Name: AZD1152
SKU: A15011
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A15011

Aurora B 抑制剂

AZD1152 是一种前药，它在血清中迅速经过磷酸酶介导的裂解，释放出 barasertib-hQPA，这是一种选择性的 Aurora B 激酶抑制剂，在急性髓性白血病（AML）患者的临床研究中显示出初步活性。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥420.00	现货
10mg	¥770.00	现货
20mg	¥1,330.00	现货
50mg	¥2,660.00	现货
100mg	¥4,760.00	现货
*10mM 1mL in DMSO**	¥560.00	现货
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Data Sheet

SDS

Other Forms of AZD1152

AZD1152-HQPA (Barasertib)

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生物活性

Discription

AZD1152 is a pro-drug that rapidly undergoes phosphatase-mediated cleavage in serum to release barasertib-hQPA, a selective Aurora B kinase inhibitor that has shown preliminary activity in clinical studies of patients with acute myeloid leukemia (AML).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A15011
分子式	C26H31FN7O6P
分子量	587.54
CAS号	722543-31-9
SMILES	CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCOP(=O)(O)O
其他名称	Barasertib, AZD-1152, AZD 1152
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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