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AZD1480

目录号: A10110

JAK1/JAK2 抑制剂

AZD1480 是一种新型的强效小分子 JAK2 抑制剂,其 IC50 为 0.26 nM。
Grouped product items
规格 价格 库存 数量
5mg
¥315.00
现货
10mg
¥525.00
现货
25mg
¥945.00
现货
50mg
¥1,715.00
现货
100mg
¥3,290.00
现货
200mg
¥5,985.00
现货
10mM * 1mL in DMSO
¥315.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

顾客使用 Adooq 产品发表的高质量科研文献
Adooq用户使用AZD1480发表的1篇文献
  • Simona Moravcova, .et al. , Life (Basel), 2021, Oct 18;11(10):1105 PMID: 34685476
  • 生物活性
    Discription AZD1480 is a novel potent small JAK2 inhibitor with an IC50 of 0.26 nM.
    Targets
    Target Value
    Cell Research
    Cell Line Type Value Description References
    产品信息
    目录号 A10110
    分子式 C14H14ClFN8
    分子量 348.8
    CAS号 935666-88-9
    SMILES CC1=CC(=NN1)NC2=NC(=NC=C2Cl)N[C@@H](C)C3=NC=C(C=N3)F
    储存条件

    Store lyophilized at -20ºC, keep desiccated.
    In lyophilized form, the chemical is stable for 36 months.
    In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

    溶解性数据
    In vitro (25°C) DMSO Warmed: 68 mg/mL (194.96 mM)
    Water Insoluble
    Ethanol Insoluble
    In vivo 30% PEG400+0.5% Tween80+5% propylene glycol 4 mg/mL
    * <1 mg/ml means slightly soluble or insoluble.
    * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
    Preparing Stock Solutions
    Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
    0.1 mM 28.67 mL 143.35 mL 286.7 mL
    0.5 mM 5.73 mL 28.67 mL 57.34 mL
    1 mM 2.87 mL 14.33 mL 28.67 mL
    5 mM 0.57 mL 2.87 mL 5.73 mL
    Useful Calculator

    This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

    Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

    • Mass

      Concentration

      Volume

      Molecular Weight

    Please check COA/MSDS for correct molecular weight.

    Calculate the dilution required to prepare a stock solution.
    This equation is commonly abbreviated as: C1V1 = C2V2

    • C1

      V1

      C2

      V2

    • Calculator Reset
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