AZD2014 (Vistusertib)

Name: AZD2014 (Vistusertib)
SKU: A11303
Price: 245 CNY
Rating: 5 (1 reviews)

目录号: A11303

mTORC1/2 抑制剂

1 篇发表文献

AZD2014 是一种口服生物利用度的哺乳动物雷帕霉素靶蛋白（mTOR）抑制剂，具有潜在的抗肿瘤活性。mTOR 激酶抑制剂。

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Grouped product items
规格	价格	库存
2mg	¥245.00	现货
5mg	¥420.00	现货
10mg	¥770.00	现货
25mg	¥1,225.00	现货
50mg	¥1,680.00	现货
100mg	¥2,730.00	现货
*10mM 1mL in DMSO**	¥350.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AZD2014 (Vistusertib)发表的1篇文献

Shuhang Dai, .et al. , Biochim Biophys Acta Mol Cell Res, 2022, Jul;1869(7):119252 PMID: 35271909

生物活性

Discription

AZD2014 is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity. mTOR kinase inhibitor.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A11303
分子式	C25H30N6O3
分子量	462.5
CAS号	1009298-59-2
SMILES	C[C@H]1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=CC=C4)C(=O)NC)N5CCOC[C@@H]5C
其他名称	AZD-2014
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	32 mg/mL (69.18 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	5% DMSO+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.62 mL	108.11 mL	216.22 mL
0.5 mM	4.32 mL	21.62 mL	43.24 mL
1 mM	2.16 mL	10.81 mL	21.62 mL
5 mM	0.43 mL	2.16 mL	4.32 mL

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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