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AZD7507是一种有效的选择性CSF-1R抑制剂(32 nM细胞活性),AZD7507被认为是一种很有前途的化合物,因为它保留了AZ683所需的效能和口服药代动力学特性。
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22 mL | 110.01 mL | 220.02 mL |
0.5 mM | 4.4 mL | 22 mL | 44 mL |
1 mM | 2.2 mL | 11 mL | 22 mL |
5 mM | 0.44 mL | 2.2 mL | 4.4 mL |
*The above data is based on the productmolecular weight 454.5. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A16886 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 454.5 |
Formula | C23H27FN6O3 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1041852-85-0 |
Synonyms | AZD-7507, AZD 7507 |
SMILES | O=C(C1=NN=C2C=C(OC)C(N3CCN(CCO)CC3)=CC2=C1NC4=CC=C(C)C=C4F)N |
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