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AZD7986，也称为INS 1007，是第二代可逆共价，有效和选择性DPP1抑制剂，潜在地可用于治疗慢性阻塞性肺疾病（COPD），其预测的人PK特性适用于每日一次人类给药。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 23.78 mL | 118.91 mL | 237.83 mL |
| 0.5 mM | 4.76 mL | 23.78 mL | 47.57 mL |
| 1 mM | 2.38 mL | 11.89 mL | 23.78 mL |
| 5 mM | 0.48 mL | 2.38 mL | 4.76 mL |
*The above data is based on the productmolecular weight 420.47. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A17095 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 420.47 |
| Formula | C23H24N4O4 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1802148-05-5 |
| Synonyms | AZD 7986, AZD-7986, INS 1007, INS-1007, INS1007 |
| SMILES | N#C[C@H](CC1=CC=C(C2=CC=C(OC(N3C)=O)C3=C2)C=C1)NC([C@H]4OCCCNC4)=O |
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