AZD8055

Name: AZD8055
SKU: A10114
Price: 210 CNY
Rating: 5 (3 reviews)

目录号: A10114

mTOR 抑制剂

3 篇发表文献

AZD8055 是一种强效、选择性且可口服生物利用度的 ATP 竞争性 mTOR 激酶抑制剂，其 IC50 为 0.8 nM。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥245.00	现货
25mg	¥490.00	现货
50mg	¥595.00	现货
100mg	¥1,015.00	现货
200mg	¥1,925.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AZD8055发表的3篇文献

L. M. C. Koene, .et al. , ACTN, 2019, June PMID: 31353861

Helga Weber, .et al. , Oncotarget, 2015, Oct 13; 6(31): 31877-31888 PMID: 26397134

Kentaro Hirose, .et al. , BMC Dev Biol, 2014, 14: 42. PMID: 25480380

生物活性

Discription

AZD8055 is a potent, selective, and orally bioavailable ATP-competitive mTOR kinase inhibitor with an IC50 of 0.8 nM.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10114
分子式	C25H31N5O4
分子量	465.5
CAS号	1009298-09-2
SMILES	C[C@H]1COCCN1C2=NC(=NC3=C2C=CC(=N3)C4=CC(=C(C=C4)OC)CO)N5CCOC[C@@H]5C
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 49 mg/mL (105.25 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (6.44 mM)
In vivo	4% DMSO+30% PEG 300+ddH2O	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.48 mL	107.41 mL	214.82 mL
0.5 mM	4.3 mL	21.48 mL	42.96 mL
1 mM	2.15 mL	10.74 mL	21.48 mL
5 mM	0.43 mL	2.15 mL	4.3 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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