AZD8329
目录号: A21081
11β-HSD1 inhibitor
AZD8329 是一种强效的 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) 抑制剂,对人类 11β-HSD1 的 IC50 为 9 nM,显示出对 11β-HSD2、17β-HSD1 和 17β-HSD3 的极佳选择性。
Discription | AZD8329 is a potent 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 9 nM for human 11β-HSD1, displays excellent selectivity versus 11β-HSD2, 17β-HSD1 and 17β-HSD3. |
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目录号 | A21081 |
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分子式 | C25H31N3O3 |
分子量 | 421.53 |
CAS号 | 1048668-70-7 |
SMILES | O=C(O)C1=CC=C(N2N=CC(C(NC3C(C4)CC5CC4CC3C5)=O)=C2C(C)(C)C)C=C1 |
其他名称 | AZD 8329, AZD-8329 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2