AZD8835

目录号: A16352
PI3Kα/PI3Kδ inhibitor
AZD8835 是一种强效且选择性的 PI3KαPI3Kδ 抑制剂,其半抑制浓度(IC50)分别为 5.7 nM 和 6.2 nM,对 PI3Kβ(IC50 431 nM)和 PI3Kγ(IC50 90 nM)具有选择性。
Grouped product items
规格 价格 库存 数量
5mg
¥245.00
现货
10mg
¥385.00
现货
25mg
¥770.00
现货
50mg
¥1,155.00
现货
100mg
¥2,170.00
现货
10mM * 1mL in DMSO
¥315.00
现货
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生物活性
Discription AZD8835 is a potent and selective inhibitor of PI3Kα and PI3Kδ with IC50 of 5.7 nM and 6.2 nM, with selectivity against PI3Kβ (IC50 431 nM) and PI3Kγ (IC50 90 nM).
Targets
Target Value
产品信息
目录号 A16352
分子式 C22H31N9O3
分子量 469.54
CAS号 1620576-64-8
SMILES O=C(N1CCC(C2=NN(CC)C(C3=NC(C4=NN=C(C(C)(C)C)O4)=C(N)N=C3)=N2)CC1)CCO
其他名称 AZD 8835, AZD-8835
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据
In vitro DMSO 83 mg/mL (176.76 mM)
Water Insoluble
Ethanol Insoluble
* <1 mg/ml means slightly soluble or insoluble.
* Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.
Preparing Stock Solutions
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 21.3 mL 106.49 mL 212.97 mL
0.5 mM 4.26 mL 21.3 mL 42.59 mL
1 mM 2.13 mL 10.65 mL 21.3 mL
5 mM 0.43 mL 2.13 mL 4.26 mL
Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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