AZD8931 (Sapitinib)

Name: AZD8931 (Sapitinib)
SKU: A10116
Price: 140 CNY
Rating: 5 (1 reviews)

目录号: A10116

pan-EGFR/pan-erbB 抑制剂

1 篇发表文献

AZD8931 是一种口服的、对 ErbB1、ErbB2 和 ErbB3 受体信号传导具有同等抑制作用的抑制剂。

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Grouped product items
规格	价格	库存
1mg	¥140.00	现货
2mg	¥175.00	现货
5mg	¥315.00	现货
10mg	¥490.00	现货
25mg	¥735.00	现货
50mg	¥1,120.00	现货
100mg	¥1,715.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用AZD8931 (Sapitinib)发表的1篇文献

Takeshi Ito, .et al. , Biochem Biophys Res Commun, 2019, in Press

生物活性

Discription

AZD8931 is an oral, equipotent inhibitor of ErbB1, ErbB2 and ErbB3 receptor signaling.

Targets

Target	Value

产品信息

目录号	A10116
分子式	C23H25ClFN5O3
分子量	473.9
CAS号	848942-61-0
SMILES	CNC(=O)CN1CCC(CC1)OC2=C(C=C3C(=C2)C(=NC=N3)NC4=C(C(=CC=C4)Cl)F)OC
其他名称	Momelotinib
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	37 mg/mL (78.07 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	30% PEG400+0.5% Tween80+5% propylene glycol	4 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.1 mL	105.51 mL	211.01 mL
0.5 mM	4.22 mL	21.1 mL	42.2 mL
1 mM	2.11 mL	10.55 mL	21.1 mL
5 mM	0.42 mL	2.11 mL	4.22 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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