AZD9898
目录号: A18959
LTC4S inhibitor
AZD9898 是一种口服活性的白三烯-C4合成酶(LTC4S,谷胱甘肽S-转移酶II)抑制剂,其 IC50 为 0.28 nM。AZD9898 可减轻 GABA 结合和肝毒性信号。AZD9898 有潜力用于治疗哮喘。
Discription | AZD9898 is an orally active leukotriene-C4 synthetase (LTC4S, glutathione S-transferase II) inhibitor, with an IC50 of 0.28 nM. AZD9898 mitigates the GABA binding and hepatic toxicity signal. AZD9898 has the potential to treat asthma. |
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目录号 | A18959 |
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分子式 | C20H19ClF3N3O4 |
分子量 | 457.83 |
CAS号 | 2042347-69-1 |
SMILES | O=C([C@@H]1[C@@H](C(C2=NC=C(N(C3=CC(Cl)=C(F)C=C3F)CC(C)(F)C)N=C2OC)=O)C1)O |
其他名称 | AZD 9898, AZD-9898 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2