Azeliragon
目录号: A20622
RAGE inhibitor
Azeliragon (TTP488) 是一种口服生物可利用的 高级糖基化终产品受体（RAGE）抑制剂，目前正在开发中，作为一种潜在治疗方法，用于减缓轻度阿尔茨海默病（AD）患者的疾病进展。Azeliragon 还能穿越 血脑屏障（BBB）。
顾客使用 Adooq 产品发表的高质量科研文献
生物活性
| Discription | Azeliragon (TTP488) is an orally bioavailable inhibitor of the receptor for advanced glycation end products (RAGE) in development as a potential treatment to slow disease progression in patients with mild Alzheimer??s disease (AD). Azeliragon also can cross the blood-brain barrier (BBB). | |||||
|---|---|---|---|---|---|---|
| Cell Research |
|
产品信息
| 目录号 | A20622 |
|---|---|
| 分子式 | C32H38ClN3O2 |
| 分子量 | 532.12 |
| CAS号 | 603148-36-3 |
| SMILES | ClC1=CC=C(C=C1)OC2=CC=C(C=C2)N3C(CCCC)=NC(C(C=C4)=CC=C4OCCCN(CC)CC)=C3 |
| 其他名称 | TTP488, TTP 488, TTP-488; PF-04494700, PF 04494700, PF04494700 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 90 mg/mL (169.13 mM) | |
| Water | Insoluble | ||
| Ethanol | 90 mg/mL | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 18.79 mL | 93.96 mL | 187.93 mL |
| 0.5 mM | 3.76 mL | 18.79 mL | 37.59 mL |
| 1 mM | 1.88 mL | 9.4 mL | 18.79 mL |
| 5 mM | 0.38 mL | 1.88 mL | 3.76 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
Keywords: 购买 Azeliragon | Azeliragon 供应商 | Azeliragon 花费 | Azeliragon 生产商 | 订购 Azeliragon | Azeliragon 代理商
| 购买 603148-36-3 | 603148-36-3 供应商 | 603148-36-3 花费 | 603148-36-3 生产商 | 订购 603148-36-3 | 603148-36-3 代理商