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AZM475271是一种有效的选择性Src激酶抑制剂，IC50为5 nM。对Flt3，KDR，Tie-2无抑制活性。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 22.58 mL | 112.88 mL | 225.76 mL |
| 0.5 mM | 4.52 mL | 22.58 mL | 45.15 mL |
| 1 mM | 2.26 mL | 11.29 mL | 22.58 mL |
| 5 mM | 0.45 mL | 2.26 mL | 4.52 mL |
*The above data is based on the productmolecular weight 442.94. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16241 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 442.94 |
| Formula | C23H27ClN4O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 476159-98-5 |
| Synonyms | AZM-475271, AZM 475271 |
| SMILES | CN1CCC(COC2=CC3=NC=NC(NC4=CC(OC)=CC=C4Cl)=C3C=C2OC)CC1 |
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