Balofloxacin
目录号: A11658
Topoisomerase 抑制剂
巴洛沙星是一种喹诺酮类抗生素。巴洛沙星的杀菌作用源于其对 DNA回旋酶 的干扰,该酶是细菌DNA合成所必需的。巴洛沙星对革兰氏阴性细菌具有有效性。它还对革兰氏阳性细菌具有增强的活性,包括 MRSA(耐甲氧西林金黄色葡萄球菌)和 肺炎链球菌。
Discription | Balofloxacin is a quinolone antibiotic. The bactericidal action of Balofloxacin results from interference with the enqyme DNA gyrase which is needed for the synthesis of bacterial DNA. Balofloxacin is efficacious against Gram-negative bacteria. It also has enhanced activity against Gram positive bacteria, including MRSA and Streptococcus pneumoniae. | |||||
---|---|---|---|---|---|---|
Targets |
|
|||||
Cell Research |
|
目录号 | A11658 |
---|---|
分子式 | C20H24FN3O4 |
分子量 | 389.42 |
CAS号 | 127294-70-6 |
SMILES | CNC1CCCN(C1)C2=C(C=C3C(=C2OC)N(C=C(C3=O)C(=O)O)C4CC4)F |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 4 mg/mL (10.26 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.68 mL | 128.4 mL | 256.79 mL |
0.5 mM | 5.14 mL | 25.68 mL | 51.36 mL |
1 mM | 2.57 mL | 12.84 mL | 25.68 mL |
5 mM | 0.51 mL | 2.57 mL | 5.14 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2