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Batimastat (BB-94)

Batimastat (BB-94)

Name: Batimastat (BB-94)
SKU: A12985

目录号: A12985

MMP 抑制剂

Batimastat (BB-94) Chemical Structure

CAS NO. 130370-60-4

Batimastat (BB-94)是多种基质金属蛋白酶（MMP）的强效合成抑制剂，包括间质胶原酶（IC50 = 3 nM），溶血素（IC50 = 20 nM），Mr 72,000型IV胶原酶（IC50 = 4） nM），92,000型IV胶原酶先生（IC50 = 4 nM）和基质溶素（IC50 = 6 nM）。它是一种低分子量（MW = 478）的肽样胶原蛋白底物类似物，由类似物结合而成，分别与MMP和催化活性锌原子结合在一起。

库存：现货

规格	价格	数量
5 mg	￥ 630.00
10 mg	￥ 980.00
25 mg	￥ 1,680.00
50 mg	￥ 2,660.00
10mM * 1mL in DMSO	￥ 1,015.00

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生物活性

靶点信息

MMP-1	MMP-2	MMP-9	MMP-7	MMP-3
3 nM	4 nM	4 nM	6 nM	20 nM

溶解度 *

In vitro (25°C)	DMSO	84 mg/mL (175.86 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	2% DMSO+40% PEG 300+2% Tween 80+ddH2O	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	20.94 mL	104.68 mL	209.36 mL
0.5 mM	4.19 mL	20.94 mL	41.87 mL
1 mM	2.09 mL	10.47 mL	20.94 mL
5 mM	0.42 mL	2.09 mL	4.19 mL

*The above data is based on the productmolecular weight 477.64. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A12985
作用机制	Inhibitor (抑制剂)
M. Wt	477.64
Formula	C23H31N3O4S2
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	130370-60-4
Synonyms	BB 94
SMILES	CC(C)C[C@H]([C@H](CSC1=CC=CS1)C(=O)NO)C(=O)N[C@@H](CC2=CC=CC=C2)C(=O)NC