BAY-678
目录号: A16866
HNE 抑制剂
BAY-678 是一种口服生物利用度高、高效、选择性强且能渗透细胞的人类中性粒细胞弹性蛋白酶(HNE)抑制剂,其 IC50 为 20 nM。BAY-678 还被提名为通过结构基因组学联盟(SGC)向公众提供的化学探针。
Discription | BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC). |
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目录号 | A16866 |
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分子式 | C20H15F3N4O2 |
分子量 | 400.35 |
CAS号 | 675103-36-3 |
SMILES | N#CC1=NC=C([C@H](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1 |
其他名称 | BAY 678, BAY678 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2