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BAY-678

目录号: A16866
HNE 抑制剂
BAY-678 是一种口服生物利用度高、高效、选择性强且能渗透细胞的人类中性粒细胞弹性蛋白酶(HNE)抑制剂,其 IC50 为 20 nM。BAY-678 还被提名为通过结构基因组学联盟(SGC)向公众提供的化学探针。
Grouped product items
规格 价格 库存 数量
5mg
¥210.00
现货
10mg
¥350.00
现货
25mg
¥840.00
现货
50mg
¥1,295.00
现货
100mg
¥1,995.00
现货
200mg
¥2,870.00
现货
10mM * 1mL in DMSO
¥210.00
现货
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重要通知:仅供研究使用。我们不向患者销售。

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生物活性
Discription BAY-678 is an orally bioavailable, highly potent, selective and cell-permeable inhibitor of human neutrophil elastase (HNE), with an IC50 of 20 nM. BAY-678 is also nominated as a chemical probe to the public via the Structural Genomics Consortium (SGC).
产品信息
目录号 A16866
分子式 C20H15F3N4O2
分子量 400.35
CAS号 675103-36-3
SMILES N#CC1=NC=C([C@H](C(C(C)=O)=C(C)N2C3=CC=CC(C(F)(F)F)=C3)NC2=O)C=C1
其他名称 BAY 678, BAY678
储存条件

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C1V1 = C2V2

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