BAY1125976
目录号: A20421
allosteric Akt1/Akt2 inhibitor
BAY1125976 是一种选择性的 allosteric Akt1/Akt2 inhibitor；在10 μM ATP条件下，对Akt1和Akt2的活性抑制的IC50值分别为5.2 nM和18 nM。
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生物活性
| Discription | BAY1125976 is a selective allosteric Akt1/Akt2 inhibitor; inhibits Akt1 and Akt2 activity with IC50 values of 5.2 nM and 18 nM at 10 μM ATP, respectively. | ||
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产品信息
| 目录号 | A20421 |
|---|---|
| 分子式 | C23H21N5O |
| 分子量 | 383.45 |
| CAS号 | 1402608-02-9 |
| SMILES | O=C(C1=NN2C(C=C1)=NC(C3=CC=C(C4(N)CCC4)C=C3)=C2C5=CC=CC=C5)N |
| 其他名称 | BAY 1125976, BAY-1125976 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 9 mg/mL (23.47 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.08 mL | 130.4 mL | 260.79 mL |
| 0.5 mM | 5.22 mL | 26.08 mL | 52.16 mL |
| 1 mM | 2.61 mL | 13.04 mL | 26.08 mL |
| 5 mM | 0.52 mL | 2.61 mL | 5.22 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1402608-02-9 | 1402608-02-9 供应商 | 1402608-02-9 花费 | 1402608-02-9 生产商 | 订购 1402608-02-9 | 1402608-02-9 代理商