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BCR-ABL-IN-2 is an inhibitor of BCR-ABL1 tyrosine kinase, with IC50s of 57 nM, 773 nm for ABL1native and ABL1T315I, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 19.9 mL | 99.52 mL | 199.05 mL |
| 0.5 mM | 3.98 mL | 19.9 mL | 39.81 mL |
| 1 mM | 1.99 mL | 9.95 mL | 19.9 mL |
| 5 mM | 0.4 mL | 1.99 mL | 3.98 mL |
*The above data is based on the productmolecular weight 502.39. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A21043 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 502.39 |
| Formula | C24H25Cl2N5O3 |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 897369-18-5 |
| SMILES | O=C([C@H]1NCC2=C(C=C(N3N=C(C(C)(C)C)C=C3NC(NC4=CC=CC(Cl)=C4Cl)=O)C=C2)C1)O |
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