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BD750, an effective immunosuppressant and a JAK3/STAT5 inhibitor, inhibits IL-2-induced JAK3/STAT5-dependent T cell proliferation, with IC50 values of 1.5 μM and 1.1 μM in mouse and human T cells, respectively.
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 36.85 mL | 184.27 mL | 368.54 mL |
| 0.5 mM | 7.37 mL | 36.85 mL | 73.71 mL |
| 1 mM | 3.69 mL | 18.43 mL | 36.85 mL |
| 5 mM | 0.74 mL | 3.69 mL | 7.37 mL |
*The above data is based on the productmolecular weight 271.34. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A22300 |
|---|---|
| M. Wt | 271.34 |
| Formula | C14H13N3OS |
| Solubility | DMSO |
| Purity | >98% |
| Storage | at -20°C 2 years |
| CAS No. | 892686-59-8 |
| SMILES | OC1=C2CCCCC2=NN1C3=NC4=CC=CC=C4S3 |
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