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BDP5290是ROCK和MRCK的有效抑制剂，对ROCK1，ROCK2，MRCKα和MRCKβ的IC50分别为5 nM，50 nM，10 nM和100 nM。
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.89 mL | 134.47 mL | 268.95 mL |
| 0.5 mM | 5.38 mL | 26.89 mL | 53.79 mL |
| 1 mM | 2.69 mL | 13.45 mL | 26.89 mL |
| 5 mM | 0.54 mL | 2.69 mL | 5.38 mL |
*The above data is based on the productmolecular weight 371.82. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A16966 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 371.82 |
| Formula | C17H18ClN7O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1817698-21-7 |
| Synonyms | BDP 5290, BDP-5290 |
| SMILES | ClC(C(C(NC1=CNN=C1C2=NC=CC=C2)=O)=N3)=CN3C4CCNCC4 |
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