Beclabuvir

目录号: A21511

HCV NS5B RNA-dependent RNA polymerase inhibitor

Beclabuvir

Beclabuvir Chemical Structure

CAS NO. 958002-33-0

Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.

库存: 现货

规格 价格 数量
1 mg
¥ 1,057.00
5 mg
¥ 3,178.00
10 mg
¥ 5,411.00
50 mg
¥ 16,226.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 15.16 mL 75.78 mL 151.55 mL
0.5 mM 3.03 mL 15.16 mL 30.31 mL
1 mM 1.52 mL 7.58 mL 15.16 mL
5 mM 0.3 mL 1.52 mL 3.03 mL

*The above data is based on the productmolecular weight 659.84. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21511
作用机制 Inhibitor (抑制剂)
M. Wt 659.84
Formula C36H45N5O5S
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 958002-33-0
Synonyms BMS-791325, BMS791325, BMS 791325
SMILES O=C(N1C2CCC1CN(C)C2)[C@@]3(CN4C5=C(C6CCCCC6)C7=CC=C(C(NS(N(C)C)(=O)=O)=O)C=C47)[C@H](C8=CC(OC)=CC=C85)C3

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