Beclabuvir
目录号: A21511
HCV NS5B RNA-dependent RNA polymerase inhibitor
Beclabuvir 是一种异构抑制剂,它结合到丙型肝炎病毒(HCV)NS5B RNA依赖性RNA聚合酶的拇指位点1,并且能够抑制来自HCV基因型1、3、4和5的重组NS5B蛋白,其IC50值小于28纳摩尔。
Discription | Beclabuvir is an allosteric inhibitor that binds to thumb site 1 of the hepatitis C virus (HCV) NS5B RNA-dependent RNA polymerase, and inhibits recombinant NS5B proteins from HCV genotypes 1, 3, 4, and 5 with IC50 of < 28 nM. | |||||
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Cell Research |
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目录号 | A21511 |
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分子式 | C36H45N5O5S |
分子量 | 659.84 |
CAS号 | 958002-33-0 |
SMILES | O=C(N1C2CCC1CN(C)C2)[C@@]3(CN4C5=C(C6CCCCC6)C7=CC=C(C(NS(N(C)C)(=O)=O)=O)C=C47)[C@H](C8=CC(OC)=CC=C85)C3 |
其他名称 | BMS-791325, BMS791325, BMS 791325 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2