Bendamustine HCl (SDX-105)

Name: Bendamustine HCl (SDX-105)
SKU: A10124
Price: 245 CNY
Rating: 5 (288 reviews)

目录号: A10124

Bendamustine Hydrochloride 是一种小分子双功能 DNA 烷化剂，它将氮芥功能与嘌呤类似物结构相结合。Bendamustine 的密集 DNA 损伤功能使其与其他用作抗增殖剂的化合物不同，这些功能被认为通过多种不同的途径促进细胞死亡，包括凋亡和有丝分裂灾难。

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Grouped product items
规格	价格	库存
25mg	¥245.00	现货
50mg	¥455.00	现货
100mg	¥805.00	现货
200mg	¥1,470.00	现货
500mg	¥2,485.00	现货
*10mM 1mL in DMSO**	¥280.00	现货
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Data Sheet

SDS

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生物活性

Discription

Bendamustine Hydrochloride is a small molecule bifunctional DNA alkylating agent, combining a nitrogen mustard functionality with a purine-analog structure. The dense DNA-damaging functionality of Bendamustine differentiates it from other compounds used as antiproliferative agents, and these functionalities are thought to promote cell death through a variety of different pathways including apoptosis and mitotic catastrophe.

Targets

Target	Value

产品信息

目录号	A10124
分子式	C16H21Cl2N3O2.HCl
分子量	394.7
CAS号	3543-75-7
SMILES	CN1C2=C(C=C(C=C2)N(CCCl)CCCl)N=C1CCCC(=O)O.Cl
其他名称	Ribomustin, Treanda, Treakisym
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	69 mg/mL (174.8 mM)
	Water	2 mg/mL (5.06 mM)
	Ethanol	15 mg/mL (37.99 mM)
In vivo	1% DMSO+30% polyethylene glycol+1% Tween 80	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.34 mL	126.68 mL	253.36 mL
0.5 mM	5.07 mL	25.34 mL	50.67 mL
1 mM	2.53 mL	12.67 mL	25.34 mL
5 mM	0.51 mL	2.53 mL	5.07 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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