Benznidazole
目录号: A17307
Benznidazol（Ro 07-1051）是一种抗寄生虫药物，对哥伦比亚T. cruzi菌株的IC50为20.35 μM，已用于治疗查加斯病。
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生物活性
| Discription | Benznidazol (Ro 07-1051) is an antiparasitic medication, with an IC50 of 20.35 μM for Colombian T. cruzi strains, and has been used in the treatment of Chagas disease. | |||||
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产品信息
| 目录号 | A17307 |
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| 分子式 | C12H12N4O3 |
| 分子量 | 260.253 |
| CAS号 | 22994-85-0 |
| SMILES | O=C(NCC1=CC=CC=C1)CN2C=CN=C2[N+]([O-])=O |
| 其他名称 | Benznidazole; NSC 299972; Radanil; Ro 07-1051; Ro 71051. |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | 46 mg/mL (176.75 mM) | |
| Water | Insoluble | ||
| Ethanol | 4 mg/mL | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 38.42 mL | 192.12 mL | 384.24 mL |
| 0.5 mM | 7.68 mL | 38.42 mL | 76.85 mL |
| 1 mM | 3.84 mL | 19.21 mL | 38.42 mL |
| 5 mM | 0.77 mL | 3.84 mL | 7.68 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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