Berberine HCl

Name: Berberine HCl
SKU: A10126
Price: 175 CNY
Rating: 5 (3 reviews)

目录号: A10126

3 篇发表文献

氯化小檗碱最近被发现对心血管系统具有多种有益效果，并具有显著的抗炎活性。小檗碱能有效降低LPS刺激的巨噬细胞内的超氧化物水平。小檗碱通过选择性抑制gp91phox表达和增强SOD活性，从而恢复细胞的氧化还原平衡。

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Grouped product items
规格	价格	库存
5g	¥175.00	现货
10g	¥315.00	现货
*10mM 1mL in DMSO**	¥175.00	现货
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Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Berberine HCl发表的3篇文献

Takashi Azuma, .et al. , SEP PURIF TECHNOL, 2019, Apr; 212: 483-489

Azuma T, .et al. , Environ Sci Pollut Res Int, 2017, Aug;24(23):19021-19030 PMID: 28660504

Azuma T, .et al. , Sci Total Environ, 2016, Apr 1;548-549:189-197 PMID: 26802347

生物活性

Discription

Berberine hydrochloride was novelly found that it has various beneficial effects on the cardiovascular system and significant anti-inflammatory activities. Berberine can effectively reduce intracellular superoxide levels in LPS-stimulated macrophages. Such a restoration of cellular redox by berberine is mediated by its selective inhibition of gp91phox expression and enhancement of SOD activity.

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10126
分子式	C20H18ClNO4
分子量	371.8
CAS号	633-65-8
SMILES	COC1=C(C2=C[N+]3=C(C=C2C=C1)C4=CC5=C(C=C4CC3)OCO5)OC.[Cl-]
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	35 mg/mL (94.13 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+30% PEG 300+ddH2O	2 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	26.9 mL	134.48 mL	268.96 mL
0.5 mM	5.38 mL	26.9 mL	53.79 mL
1 mM	2.69 mL	13.45 mL	26.9 mL
5 mM	0.54 mL	2.69 mL	5.38 mL

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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