BETd-260
目录号: A12563
BET degrader
BETd-260 是一种基于 PROTAC 技术的强效 BET 降解剂,在 RS4;11 白血病细胞系中对 BRD4 蛋白的活性低至 30 pM。
Discription | BETd-260 is a potent BET degrader based on PROTAC technology, with as low as 30 pM against BRD4 protein in RS4;11 leukemia cell line. | |||||
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Targets |
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Cell Research |
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目录号 | A12563 |
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分子式 | C43H46N10O6 |
分子量 | 798.89 |
CAS号 | 2093388-62-4 |
SMILES | CCN1N=C(C2CC2)C=C1NC3=NC(C(NCCCCCC4=CC=CC5=C4CN(C6C(NC(CC6)=O)=O)C5=O)=O)=NC7=C3C8=CC(OC)=C(C9=C(C)ON=C9C)C=C8N7 |
其他名称 | BETd260, BETd 260, ZBC 260, ZBC-260, ZBC260 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2