BG45
目录号: A11361
HDAC 抑制剂
BG45 是一种 HDAC I 类抑制剂,对 HDAC3 具有选择性(IC50 = 289 nM)。它对 HDAC1、HDAC2 和 HDAC6 的抑制作用大大降低(IC50 分别为 2, 2.2 和 >20 μM)。
Discription | BG45 is an HDAC class I inhibitor with selectivity for HDAC3 (IC50 = 289 nM). It inhibits HDAC1, HDAC2, and HDAC6 with greatly reduced potency (IC50s = 2, 2.2, and >20 μM, respectively). | |||||
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Cell Research |
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目录号 | A11361 |
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分子式 | C11H10N4O |
分子量 | 214.22 |
CAS号 | 926259-99-6 |
SMILES | NC1=CC=CC=C1/N=C(O)/C2=CN=CC=N2 |
其他名称 | BG 45, BG-45 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 40 mg/mL (186.72 mM) | |
Water | Insoluble | ||
Ethanol | Warmed: 2 mg/mL (9.33 mM) | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 46.68 mL | 233.4 mL | 466.81 mL |
0.5 mM | 9.34 mL | 46.68 mL | 93.36 mL |
1 mM | 4.67 mL | 23.34 mL | 46.68 mL |
5 mM | 0.93 mL | 4.67 mL | 9.34 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2