BI6727 (Volasertib)

Name: BI6727 (Volasertib)
SKU: A10135
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A10135

PLK 抑制剂

1 篇发表文献

BI6727 是一种高效且选择性的 polo-like kinase (PLK) 1 抑制剂（酶 IC50 = 0.87 nM，EC50 = 11-37 nM，针对一系列癌症细胞系）。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥350.00	现货
5mg	¥490.00	现货
10mg	¥910.00	现货
25mg	¥1,995.00	现货
50mg	¥3,115.00	现货
100mg	¥5,215.00	现货
500mg	¥11,025.00	现货
*10mM 1mL in DMSO**	¥840.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用BI6727 (Volasertib)发表的1篇文献

Xiaofei Xin, .et al. , ACS Appl Mater Interfaces, 2019, 2019 PMID: 30933478

生物活性

Discription

BI6727 is a highly potent and selective polo-like kinase (PLK) 1 inhibitor (enzyme IC50 = 0.87 nM, EC50 = 11-37 nM on a panel of cancer cell lines).

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10135
分子式	C34H50N8O3
分子量	618.8
CAS号	755038-65-4
SMILES	CC[C@@H]1C(=O)N(C2=CN=C(N=C2N1C(C)C)NC3=C(C=C(C=C3)C(=O)NC4CCC(CC4)N5CCN(CC5)CC6CC6)OC)C
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	Warmed: 19 mg/mL (30.7 mM)
	Water	Insoluble
	Ethanol	Insoluble
In vivo	4% DMSO+corn oil	1 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	16.16 mL	80.8 mL	161.6 mL
0.5 mM	3.23 mL	16.16 mL	32.32 mL
1 mM	1.62 mL	8.08 mL	16.16 mL
5 mM	0.32 mL	1.62 mL	3.23 mL

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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