Bibf1120 (Nintedanib)

Name: Bibf1120 (Nintedanib)
SKU: A10137
Price: 210 CNY
Rating: 5 (3 reviews)

目录号: A10137

VEGFR 抑制剂

3 篇发表文献

BIBF1120（Vargatef）是一种新型的三重血管激酶抑制剂，能同时抑制三种生长因子受体：VEGFR、PDGF 和 FGFR。

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Grouped product items
规格	价格	库存
5mg	¥210.00	现货
10mg	¥315.00	现货
50mg	¥385.00	现货
100mg	¥595.00	现货
200mg	¥945.00	现货
500mg	¥1,820.00	现货
1g	¥3,500.00	现货
*10mM 1mL in DMSO**	¥315.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用Bibf1120 (Nintedanib)发表的3篇文献

Yan Yang, .et al. , J Thorac Dis, 2024, Feb 29;16(2):1128-1140 PMID: 38505034

Majid Momeny, .et al. , Life Sci, 2021, Dec 15;287:120100 PMID: 34715143

Chun-Jung Chang, .et al. , Biochem Pharmacol, 2021, Jan;183:114356 PMID: 33285108

生物活性

Discription

BIBF1120 (Vargatef) is a novel triple angiokinase inhibitor that inhibits three growth factor receptors simultaneously: VEGFR, PDGF and FGFR.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10137
分子式	C31H33N5O4
分子量	539.6
CAS号	928326-83-4, 656247-17-5
SMILES	CN1CCN(CC1)CC(=O)N(C)C2=CC=C(C=C2)N/C(=C\3/C4=C(C=C(C=C4)C(=O)OC)NC3=O)/C5=CC=CC=C5
其他名称	Vargatef
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	6 mg/mL (11.11 mM)
	Water	Insoluble
	Ethanol	3 mg/mL (5.55 mM)
In vivo	5% DMSO+40% PEG 300+2% Tween 80+ddH2O	0.23 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	18.53 mL	92.66 mL	185.32 mL
0.5 mM	3.71 mL	18.53 mL	37.06 mL
1 mM	1.85 mL	9.27 mL	18.53 mL
5 mM	0.37 mL	1.85 mL	3.71 mL

Useful Calculator

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Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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