BIBR 953 (Dabigatran, Pradaxa)

Name: BIBR 953 (Dabigatran, Pradaxa)
SKU: A10138
Price: 210 CNY
Rating: 5 (1 reviews)

目录号: A10138

Thrombin 抑制剂

1 篇发表文献

BIBR 953（达比加群，普拉达沙）是一种高度选择性、可逆的、强效的凝血酶抑制剂，以前体药物达比加群依他希拉特的形式口服给药。在血栓形成的动物模型中显示出抗血栓效果，具有快速的起效时间和可预测的药效学反应。

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Grouped product items
规格	价格	库存
1mg	¥210.00	现货
2mg	¥315.00	现货
5mg	¥525.00	现货
10mg	¥945.00	现货
25mg	¥1,925.00	现货
50mg	¥3,115.00	现货
100mg	¥4,830.00	现货
500mg	¥10,255.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of BIBR 953 (Dabigatran, Pradaxa)

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用BIBR 953 (Dabigatran, Pradaxa)发表的1篇文献

Tanaka M, .et al. , J Pharmacol Sci, 2016, Jul;131(3):162-71 PMID: 27426918

生物活性

Discription

BIBR 953 (Dabigatran, Pradaxa) is a highly selective, reversible, and potent thrombin inhibitor and is orally available as the prodrug, dabigatran etexilate. It has shown antithrombotic efficacy in animal models of thrombosis, with a rapid onset of action and predictable pharmacodynamic response.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10138
分子式	C25H25N7O3
分子量	471.5
CAS号	211914-51-1
SMILES	CN1C2=C(C=C(C=C2)C(=O)N(CCC(=O)O)C3=CC=CC=N3)N=C1CNC4=CC=C(C=C4)C(=N)N
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro (25°C)	DMSO	<1 mg/mL
	Water	29 mg/mL (61.5 mM)
	Ethanol	0.01 mg/mL (0.02 mM)
In vivo	10% Trifluoroacetic acid water solution	31 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	21.21 mL	106.04 mL	212.09 mL
0.5 mM	4.24 mL	21.21 mL	42.42 mL
1 mM	2.12 mL	10.6 mL	21.21 mL
5 mM	0.42 mL	2.12 mL	4.24 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

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* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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