(E/Z)-BIBW2992 (E/Z-Afatinib)

Name: (E/Z)-BIBW2992 (E/Z-Afatinib)
SKU: A10141
Price: 140 CNY
Rating: 5 (6 reviews)

目录号: A10141

EGFR 抑制剂

6 篇发表文献

BIBW2992（阿法替尼）是一种酪氨酸激酶抑制剂（TKI），可以不可逆地抑制人类表皮生长因子受体2（Her2）和表皮生长因子受体（EGFR）激酶。

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规格	价格	库存
100mg	¥140.00	现货
200mg	¥210.00	现货
500mg	¥280.00	现货
1g	¥385.00	现货
*10mM 1mL in DMSO**	¥140.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

Other Forms of (E/Z)-BIBW2992 (E/Z-Afatinib)

顾客使用 Adooq 产品发表的高质量科研文献

Adooq用户使用(E/Z)-BIBW2992 (E/Z-Afatinib)发表的6篇文献

Song Han, .et al. , Neoplasia, 2025, Jan:59:101070 PMID: 39541736

Sang-Hyun Lee, .et al. , NPJ Precis Oncol, 2024, May 21;8(1):111 PMID: 38773241

Yi-Ru Pan, .et al. , Int J Biol Sci, 2023, May 21;19(9):2772-2786 PMID: 37324940

Aya Hasan Alshammari, .et al. , Biochem Pharmacol, 2022, Mar;197:114914 PMID: 35041812

Van Sebille YZ, .et al. , Exp Biol Med (Maywood), 2019, Jun 11:1535370219855334 PMID: 31184924

Fujita KI, .et al. , J Pharm Sci, 2017, Sep;106(9):2632-2641 PMID: 28479358

生物活性

Discription

BIBW2992 (Afatinib) is tyrosine kinase inhibitor (TKI) that irreversibly inhibits human epidermal growth factor receptor 2 (Her2) and epidermal growth factor receptor (EGFR) kinases.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10141
分子式	C24H25ClFN5O3
分子量	485.9
CAS号	439081-18-2
SMILES	CN(C)C/C=C/C(=O)NC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC(=C(C=C3)F)Cl)O[C@H]4CCOC4
其他名称	Tomtovok
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

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