BIIB021

Name: BIIB021
SKU: A10143

目录号: A10143

HSP90 抑制剂

Product Citations (2)

BIIB021 Chemical Structure

CAS NO. 848695-25-0

BIIB021是一种口服全合成Hsp90抑制剂，可选择性和有效地抑制分子伴侣Hsp90。

库存：现货

规格	价格	数量
5 mg	￥ 385.00
10 mg	￥ 560.00
50 mg	￥ 1,470.00
100 mg	￥ 2,240.00
10mM * 1mL in DMSO	￥ 420.00

或

添加到收藏

产品仅用于科学研究，不针对患者销售，望谅解.

产品详情

生物活性

BIIB021是一种口服全合成Hsp90抑制剂，可选择性和有效地抑制分子伴侣Hsp90。

靶点信息

HSP90	HSP90
1.7 nM(Ki)	38 nM(EC50)

溶解度 *

In vitro (25°C)	DMSO	60 mg/mL (188.22 mM)
	Water	Insoluble
	Ethanol	2 mg/mL (6.27 mM)
In vivo	30% propylene glycol, 5% Tween 80, 65% D5W	28 mg/mL
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	31.37 mL	156.84 mL	313.68 mL
0.5 mM	6.27 mL	31.37 mL	62.74 mL
1 mM	3.14 mL	15.68 mL	31.37 mL
5 mM	0.63 mL	3.14 mL	6.27 mL

*The above data is based on the productmolecular weight 318.8 . Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A10143
作用机制	Inhibitor (抑制剂)
M. Wt	318.8
Formula	C14H15ClN6O
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	848695-25-0
Synonyms	CNF2024
SMILES	CC1=CN=C(C(=C1OC)C)CN2C=NC3=C2N=C(N=C3Cl)N