BIO-acetoxime

Name: BIO-acetoxime
SKU: A15555

目录号: A15555

GSK-3 抑制剂

BIO-acetoxime Chemical Structure

CAS NO. 667463-85-6

BIO-acetoxime是一种有效的双重GSK3α/β抑制剂，IC50为10 nM，选择性比CDK5/p25，CDK2/cyclin A和 CDK1/cyclin B高240倍以上。

库存：现货

规格	价格	数量
2 mg	￥ 350.00
5 mg	￥ 525.00

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生物活性

BIO-acetoxime是一种有效的双重GSK3α/β抑制剂，IC50为10 nM，选择性比CDK5/p25，CDK2/cyclin A和 CDK1/cyclin B高240倍以上。

靶点信息

GSK-3α	GSK-3β
10 nM	10 nM

溶解度 *

In vitro	DMSO	Warmed: 18 mg/mL (45.2 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

制备储备液

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	25.11 mL	125.56 mL	251.12 mL
0.5 mM	5.02 mL	25.11 mL	50.22 mL
1 mM	2.51 mL	12.56 mL	25.11 mL
5 mM	0.5 mL	2.51 mL	5.02 mL

*The above data is based on the productmolecular weight 398.21. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

化学数据

目录号	A15555
作用机制	Inhibitor (抑制剂)
M. Wt	398.21
Formula	C18H12BrN3O3
Purity	>99%
Storage	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.
CAS No.	667463-85-6
Synonyms	MolPort-023-276-964, 667463-85-6, AKOS024457841, AKOS025295610
SMILES	CC(=O)ONC1=C2C=CC=CC2=NC1=C3C4=C(C=C(C=C4)Br)NC3=O