BIO-acetoxime
目录号: A15555
GSK-3 抑制剂
BIO-acetoxime (BIA) 是一种强效且选择性的 GSK-3 抑制剂,对 GSK-3α/β 的 IC50 均为 10 nM。BIO-acetoxime 具有抗癫痫和抗感染活性。
Discription | BIO-acetoxime (BIA) is a potent and selective GSK-3 inhibitor, with IC50s of both 10 nM for GSK-3α/β. BIO-acetoxime has anticonvulsant and anti-infection activity. | ||
---|---|---|---|
Targets |
|
目录号 | A15555 |
---|---|
分子式 | C18H12BrN3O3 |
分子量 | 398.21 |
CAS号 | 667463-85-6 |
SMILES | CC(=O)ONC1=C2C=CC=CC2=NC1=C3C4=C(C=C(C=C4)Br)NC3=O |
其他名称 | MolPort-023-276-964, 667463-85-6, AKOS024457841, AKOS025295610 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | Warmed: 18 mg/mL (45.2 mM) | |
Water | Insoluble | ||
Ethanol | Insoluble | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 25.11 mL | 125.56 mL | 251.12 mL |
0.5 mM | 5.02 mL | 25.11 mL | 50.22 mL |
1 mM | 2.51 mL | 12.56 mL | 25.11 mL |
5 mM | 0.5 mL | 2.51 mL | 5.02 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2