bio-THZ1
目录号: A18559
covalent CDK7 抑制剂
bio-THZ1 是 THZ1 的生物素化版本,能够不可逆地结合到 CDK7。THZ1 是一种选择性且高效的共价 CDK7 抑制剂,其 IC50 为 3.2 nM。
Discription | bio-THZ1 is a biotinylated version of THZ1 and binds irreversibly to CDK7. THZ1 is a selective and potent covalent CDK7 inhibitor with an IC50 of 3.2 nM. |
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目录号 | A18559 |
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分子式 | C52H65ClN12O8S |
分子量 | 1053.67 |
CAS号 | 1604811-14-4 |
SMILES | O=C(NCCOCCOCCOCCNC(NCCCN(C)C/C=C/C(NC1=CC=C(C(NC2=CC=CC(NC3=NC=C(Cl)C(C4=CNC5=C4C=CC=C5)=N3)=C2)=O)C=C1)=O)=O)CCCC[C@@H]6SC[C@]([C@]6([H])N7)([H])NC7=O |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2