微信关注
Total item
Cart Subtotal
￥ 0.00 产品详情
BMN-673是核酶聚（ADP-核糖）聚合酶（PARP）的口服生物利用抑制剂，无细胞试验中对PARP1的IC50为0.57 nM。它也是有效的PARP-2抑制剂，但不抑制PARG，对PTEN突变型高度敏感。具有潜在的抗肿瘤活性。
靶点信息
| PARP (Cell-free assay) | ||||
| 0.58 nM |
| In vitro | DMSO | Warmed: 38 mg/mL (99.9 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
|
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
|||
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.29 mL | 131.46 mL | 262.92 mL |
| 0.5 mM | 5.26 mL | 26.29 mL | 52.58 mL |
| 1 mM | 2.63 mL | 13.15 mL | 26.29 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
*The above data is based on the productmolecular weight 380.35. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
| 目录号 | A11243 |
|---|---|
| 作用机制 | Inhibitor (抑制剂) |
| M. Wt | 380.35 |
| Formula | C19H14F2N6O |
| Purity | >99% |
| Storage | Store lyophilized at -20ºC, keep desiccated. |
| CAS No. | 1207456-01-6 |
| Synonyms | BMN-673, BMN 673 |
| SMILES | CN1C(=NC=N1)[C@@H]2[C@H](N=C3C=C(C=C4C3=C2NNC4=O)F)C5=CC=C(C=C5)F |
产品标签
Product Questions
Product Questions
No Questions
Keywords:购买 BMN673 | BMN673 供应商 | 订购 BMN673 | BMN673 价格 | BMN673 生产商 | 订单 BMN673 | BMN673 代理商 | 购买 1207456-01-6| 1207456-01-6 供应商 | 订购 1207456-01-6 | 1207456-01-6 价格 | 1207456-01-6 生产商 | 订单 1207456-01-6 | 1207456-01-6 代理商|buy BMN673 | BMN673 Supplier | purchase BMN673 | BMN673 cost | BMN673 manufacturer | order BMN673 | BMN673 distributor | buy 1207456-01-6| 1207456-01-6 Supplier | purchase 1207456-01-6 | 1207456-01-6 cost | 1207456-01-6 manufacturer | order 1207456-01-6 | 1207456-01-6 distributor