Talazoparib (BMN673)
BMN-673 是一种口服生物利用度的抑制剂，针对核酶多聚(ADP-核糖)聚合酶（PARP）具有潜在的抗肿瘤活性。
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生物活性
| Discription | BMN-673 is an orally bioavailable inhibitor of the nuclear enzyme poly(ADP-ribose) polymerase (PARP) with potential antineoplastic activity. | |||||
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| Cell Research |
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产品信息
| 目录号 | A11243 |
|---|---|
| 分子式 | C19H14F2N6O |
| 分子量 | 380.35 |
| CAS号 | 1207456-01-6 |
| SMILES | CN1C(=NC=N1)[C@@H]2[C@H](N=C3C=C(C=C4C3=C2NNC4=O)F)C5=CC=C(C=C5)F |
| 其他名称 | BMN-673, BMN 673 |
| 储存条件 | Store lyophilized at -20ºC, keep desiccated. |
溶解性数据
| In vitro | DMSO | Warmed: 38 mg/mL (99.9 mM) | |
| Water | Insoluble | ||
| Ethanol | Insoluble | ||
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* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
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Preparing Stock Solutions
| Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
|---|---|---|---|
| 0.1 mM | 26.29 mL | 131.46 mL | 262.92 mL |
| 0.5 mM | 5.26 mL | 26.29 mL | 52.58 mL |
| 1 mM | 2.63 mL | 13.15 mL | 26.29 mL |
| 5 mM | 0.53 mL | 2.63 mL | 5.26 mL |
Useful Calculator
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2
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| 购买 1207456-01-6 | 1207456-01-6 供应商 | 1207456-01-6 花费 | 1207456-01-6 生产商 | 订购 1207456-01-6 | 1207456-01-6 代理商