产品详情
BMS-1166 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 14.76 mL | 73.79 mL | 147.59 mL |
0.5 mM | 2.95 mL | 14.76 mL | 29.52 mL |
1 mM | 1.48 mL | 7.38 mL | 14.76 mL |
5 mM | 0.3 mL | 1.48 mL | 2.95 mL |
*The above data is based on the productmolecular weight 677.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A21481 |
---|---|
作用机制 | Inhibitor (抑制剂) |
M. Wt | 677.57 |
Formula | C36H34Cl2N2O7 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 2113650-05-6 |
Synonyms | BMS 1166 Hydrochloride; BMS1166 Hydrochloride; BMS-1166 HCl; BMS 1166 HCl; BMS1166 HCl |
SMILES | O=C(O)[C@@H]1N(CC2=CC(Cl)=C(OCC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C)C=C2OCC6=CC=CC(C#N)=C6)C[C@H](O)C1.Cl |
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