BMS-1166 hydrochloride

目录号: A21481

PD-1/PD-L1 interaction inhibitor

BMS-1166 hydrochloride

BMS-1166 hydrochloride Chemical Structure

CAS NO. 2113650-05-6

BMS-1166 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.

库存: 现货

规格 价格 数量
5 mg
¥ 3,465.00
10 mg
¥ 5,971.00
50 mg
¥ 17,710.00
100 mg
¥ 35,420.00
Warning 产品仅用于科学研究,不针对患者销售,望谅解.

产品详情

BMS-1166 hydrochloride is a potent PD-1/PD-L1 interaction inhibitor with an IC50 of 1.4 nM. BMS-1166 antagonizes the inhibitory effect of PD-1/PD-L1 immune checkpoint on T cell activation.
Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.1 mM 14.76 mL 73.79 mL 147.59 mL
0.5 mM 2.95 mL 14.76 mL 29.52 mL
1 mM 1.48 mL 7.38 mL 14.76 mL
5 mM 0.3 mL 1.48 mL 2.95 mL

*The above data is based on the productmolecular weight 677.57. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.

目录号 A21481
作用机制 Inhibitor (抑制剂)
M. Wt 677.57
Formula C36H34Cl2N2O7
Purity >99%
Storage

Store lyophilized at -20ºC, keep desiccated.
In lyophilized form, the chemical is stable for 36 months.
In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

CAS No. 2113650-05-6
Synonyms BMS 1166 Hydrochloride; BMS1166 Hydrochloride; BMS-1166 HCl; BMS 1166 HCl; BMS1166 HCl
SMILES O=C(O)[C@@H]1N(CC2=CC(Cl)=C(OCC3=CC=CC(C4=CC=C(OCCO5)C5=C4)=C3C)C=C2OCC6=CC=CC(C#N)=C6)C[C@H](O)C1.Cl

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