BMS-687453
目录号: A15836
PPAR 激动剂
BMS-687453 是一种强效且选择性的过氧化物酶体增殖物激活受体(PPAR)α激动剂,对人类PPARα的EC(50)为10 nM,并且在PPAR-GAL4转录激活试验中,相对于人类PPARγ具有约410倍的选择性。
Discription | BMS-687453 is a potent and selective peroxisome proliferator activated receptor (PPAR) alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays. | |||||
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Cell Research |
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目录号 | A15836 |
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分子式 | C22H21ClN2O6 |
分子量 | 444.86 |
CAS号 | 1000998-59-3 |
SMILES | O=C(O)CN(CC1=CC=CC(OCC2=C(C)OC(C3=CC=C(Cl)C=C3)=N2)=C1)C(OC)=O |
其他名称 | BMS687453, BMS 687453 |
储存条件 | Store lyophilized at -20ºC, keep desiccated. |
In vitro | DMSO | 80 mg/mL (179.83 mM) | |
Water | Insoluble | ||
Ethanol | 80 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
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0.1 mM | 22.48 mL | 112.39 mL | 224.79 mL |
0.5 mM | 4.5 mL | 22.48 mL | 44.96 mL |
1 mM | 2.25 mL | 11.24 mL | 22.48 mL |
5 mM | 0.45 mL | 2.25 mL | 4.5 mL |
Calculate the dilution required to prepare a stock solution. This equation is commonly abbreviated as: C1V1 = C2V2