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BMS-687453是一种有效的选择性过氧化物酶体增殖物激活受体(PPAR)α激动剂,对人PPARα的EC(50)为10 nM,在PPAR-GAL4反式激活试验中,选择性是对人PPARgamma的410倍。
In vitro | DMSO | 80 mg/mL (179.83 mM) | |
Water | Insoluble | ||
Ethanol | 80 mg/mL | ||
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations. |
Concentration / Solvent Volume / Mass | 1 mg | 5 mg | 10 mg |
---|---|---|---|
0.1 mM | 22.48 mL | 112.39 mL | 224.79 mL |
0.5 mM | 4.5 mL | 22.48 mL | 44.96 mL |
1 mM | 2.25 mL | 11.24 mL | 22.48 mL |
5 mM | 0.45 mL | 2.25 mL | 4.5 mL |
*The above data is based on the productmolecular weight 444.86. Batch specific molecular weights may vary from batch to batch due to solvent of hydration, which will affect the solvent volumes required to prepare stock solutions.
目录号 | A15836 |
---|---|
作用机制 | Agonist (激动剂) |
M. Wt | 444.86 |
Formula | C22H21ClN2O6 |
Purity | >99% |
Storage | Store lyophilized at -20ºC, keep desiccated. |
CAS No. | 1000998-59-3 |
Synonyms | BMS687453, BMS 687453 |
SMILES | O=C(O)CN(CC1=CC=CC(OCC2=C(C)OC(C3=CC=C(Cl)C=C3)=N2)=C1)C(OC)=O |
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