BMS-708163 (Avagacestat)

Name: BMS-708163 (Avagacestat)
SKU: A10157
Price: 350 CNY
Rating: 5 (288 reviews)

目录号: A10157

Gamma-secretase 抑制剂

BMS-708163 是一种口服 伽玛分泌酶抑制剂，专为选择性抑制 淀粉样β蛋白 合成而设计。

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Grouped product items
规格	价格	库存
1mg	¥350.00	现货
5mg	¥735.00	现货
10mg	¥1,365.00	现货
25mg	¥3,045.00	现货
50mg	¥4,550.00	现货
100mg	¥6,510.00	现货
500mg	¥13,195.00	现货
*10mM 1mL in DMSO**	¥945.00	现货
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重要通知：仅供研究使用。我们不向患者销售。

Data Sheet

SDS

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生物活性

Discription

BMS-708163 is an oral gamma secretase inhibitor designed for selective inhibition of amyloid beta synthesis.

Targets

Target	Value

Cell Research

Cell Line	Type	Value	Description	References

产品信息

目录号	A10157
分子式	C20H17ClF4N4O4S
分子量	520.8
CAS号	1146699-66-2
SMILES	C1=CC(=CC=C1S(=O)(=O)N(CC2=C(C=C(C=C2)C3=NOC=N3)F)[C@H](CCC(F)(F)F)C(=O)N)Cl
储存条件	Store lyophilized at -20ºC, keep desiccated. In lyophilized form, the chemical is stable for 36 months. In solution, store at -20ºC and use within 3 months to prevent loss of potency. Aliquot to avoid multiple freeze/thaw cycles.

溶解性数据

In vitro	DMSO	90 mg/mL (172.78 mM)
	Water	Insoluble
	Ethanol	Insoluble
* <1 mg/ml means slightly soluble or insoluble. * Please note that Adooq tests the solubility of all compounds in-house, and the actual solubility may differ slightly from published values. This is normal and is due to slight batch-to-batch variations.

Preparing Stock Solutions

Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
0.1 mM	19.2 mL	96.01 mL	192.01 mL
0.5 mM	3.84 mL	19.2 mL	38.4 mL
1 mM	1.92 mL	9.6 mL	19.2 mL
5 mM	0.38 mL	1.92 mL	3.84 mL

Useful Calculator

This calculator helps you calculate mass of compound based on solution concentration, volume and molecular weight in a specific solution using the formula:

Mass (mg) = Concentration (mM) × Volume (mL) × Molecular Weight (g/mol)

Calculate Reset

* Please check COA/MSDS for correct molecular weight.

Calculate the dilution required to prepare a stock solution.
This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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